Research Profiles: 

Prevention and treatment of dental caries in children and its pathogenesis; vital pulp preservation and pulp regeneration; Diagnosis and treatment of dental genetic diseases; Diagnosis and treatment of dental trauma in children

Research Expertise

Research Theme: 

1. The expansion implements of Guidance on prevention and appropriate clinical treatment of severe early childhood caries

2. Variation of oral microbiome metabolism during caries development and its relationship with caries mechanism

3. The microbial influence of caries of the deciduous molars on the risk of caries in the first permanent molars

4. Application of pulp revascularization in the treatment of young permanent teeth pulp

5. The prognosis and healing mechanism of dental trauma in children

Academic Publications

1.Jingjing Zhang, Nan Wang, Xuemei Gao, Man Qin*. Orthodontic Extrusion with Fixed Appliances for Treatment of Intrusive Luxation Injuries: A Prospective Study of 28 Permanent Maxillary Incisors. Int J Paediatr Dent. First published: 03 August 2024, https://doi.org/10.1111/ipd.13254. 

2.Jing Tian, Bingqian Zhao, Jingyan Wang, Wenbin Du, Wenli Ma, Bin Xia, He Xu, Tsute Chen, Xuesong He, Man Qin*. The short- term impact of comprehensive caries treatment on the supragingival microbiome of severe early childhood caries. Int J Paediatr Dent. 2024;34:505–515. doi:10.1111/ipd.13151. 

3.Guiyan Wang, Ning Yuan, Jun Zhang, Man Qin, Suwei Dong*, and Yuguang Wang*. Visible light cross-linking and bioactive peptides loaded integrated hydrogel with sequential release to accelerate wound healing complicated by bacterial infection. Nano Research, 2024,17(3):1737-1747. https://doi.org/10.1007/s12274-023-5958-6. 

4.Weihua Shi, Jing Tian, He Xu and Man Qin*. Microbial Relationship of Carious Deciduous Molars and Adjacent First Permanent Molars. Microorganisms. 2023,11,2461. https://doi.org/10.3390/microorganisms11102461. 

5.Jing Tian, Daniel R. Utter, Lujia Cen, Pu-Ting Dong, Wenyuan Shi, Batbileg Bor, Man Qin, Jeffrey S. McLean, Xuesong He*. Acquisition of Arginine Deiminase System benefits epiparasitic Saccharibacteria and its host bacteria in mammalian niche environment. P Natl Accd Sci USA. 2022 119 (2) e 2114909119 ; https://doi.org/10.1073/pnas.2114909119.

6.He Xu, Bijun Tian, Weihua Shi, Jing Tian, Wenjun Wang, Man Qin*. Maturation of oral microbiota during primary teeth eruption: A longitudinal, preliminary study. Journal of Oral Microbiology. 14:1, 2051352. DOI: 10.1080/20002297.2022.2051352 

7.Guiyan Wang, Ning Yuan, Ningyu Li, Qijia Wei, Yuping Qian, Jun Zhang, Man Qin, Yuguang Wang,* and Suwei Dong*. Vascular Endothelial Growth Factor Mimetic Peptide and Parathyroid Hormone (1-34) Delivered via a Blue-Light-CurableHydrogel Synergistically Accelerate Bone Regeneration. ACS applied materials & interfaces. https://doi.org/10.1021/acsami.2c06159 2022. 

8.Yi Yang, Junxia Zhu, Yuta Chiba, Satoshi Fukumoto, Man Qin, Xin Wang*. Enamel defects of Axenfeld-Rieger syndrome and the role of PITX2 in its pathogenesis. Oral Diseases. 2022;00:1–11. https://doi.org/10.1111/odi.14315

9.He Xu, Bijun Tian, Weihua Shi, Jing Tian, Xuexi Zhang, Jin Zeng and Man Qin*. A Correlation Study of the Microbiota Between Oral Cavity and Tonsils in Children With Tonsillar Hypertrophy. Frontiers in Cellular and Infection Microbiology, published: 28 January 2022. 11:724142. doi:10.3389/fcimb. 2021. 724142. 

10.Jing Tian, Weihua Shi, He Xu, Guiyan Wang, Xuesong He, Feng Chen* and Man Qin*. Differences in Sole Carbon Source Utilization of the Dental Plaque Microbiota Between Caries-Free and Caries-Affected Children. Front. Microbiol. published: 20 March 2020.doi: 10.3389/fmicb.2020.00458.